Plants are the primary food producers and they comprise the essential wellspring of carbon, nutrients, minerals, protein and unsaturated fats. Plant proteins can help in anticipation of cardiovascular illness, disease, bone misfortune and diabetes. Cereal grains, legumes including oil-seed provide proteins to the entire animal kingdom. Plant enzymes like proteases, amylases, cellulose and lipase are useful in the digestion of raw food. Plants have been used to treat many ailments from time immemorial. Moreover, much work has been done to study the therapeutic effect of secondary metabolites from plants rather than the primary metabolites namely proteins, carbohydrates, enzymes and lipids. This review stresses upon the use of plant proteins and enzymes as a whole for treating diseases/disorders rather than the secondary metabolites.